Bioss Inc.'s RSPO3 Polyclonal Antibody, Biotin Conjugated is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The RSPO3 Polyclonal Antibody, Biotin Conjugated was generated using R-Spondin 3, and RSPO3 as the antigen and it reacts with Human.
Description
Activator of the beta-catenin signaling cascade, leading to TCF-dependent gene activation. Acts both in the canonical Wnt/beta-catenin-dependent pathway, possibly via a direct interaction with Wnt proteins, and in a Wnt-independent beta catenin pathway through a receptor signaling pathway that may not use frizzled/LRP receptors. Acts as a ligand for frizzled FZD8 and LRP6. May negatively regulate the TGF-beta pathway